RT Journal Article SR Electronic T1 Efficacy of bronchoscopic closure of broncho-pleural fistula with Amplatzer devices: Long term follow-up JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P501 VO 44 IS Suppl 58 A1 Oren Fruchter A1 Bayya Abed El Raouf A1 Milton Saute A1 Elchanan Bruckheimer A1 Mordechai Kramer YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P501.abstract AB Objective: We have developed a minimally invasive method of bronchoscopic closure of Broncho-pleural fistula using Amplazer devices (AD) and Amplazer vascular plugs (AVP). The aim of the present report was to explore the long term outcome of patients treated by this novel modality.Methods:A total of 31 central BPF in 31 patients were sealed under moderate sedation bronchoscopically by either AD (N = 19) or (N = 12). The average follow-up period was 17.6 months (range 1-68 months)Results: The main etiology for BPF was surgery (N = 24). The underlying disease was lung cancer either primary (N = 20) or metastatic (n = 2). The immediate success rate was 96% as symptoms related to BPF disappeared in 30/31 of the patients. At follow-up, 14 patients (45%) are still alive. Out of 12 patients with late mortality, in 5 patients (41 %) the death was directly related to cancer relapse.Conclusion: Endobronchial closure of BPF using both types of Amplatzer occluders (AD, AVP) is a minimally invasive effective modality of treatment with high safety profile and satisfactory long term outcome.