RT Journal Article
SR Electronic
T1 A feasibility study of pulmonary rehabilitation at home in patients with lung cancer or malignant pleural mesothelioma treated by (radio-)chemotherapy
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1714
VO 44
IS Suppl 58
A1 Cecile Olivier
A1 Julie Delourme
A1 Alexis Cortot
A1 Marianne Gierczynski
A1 Sophie Peres
A1 Christophe Heron
A1 Anne Hoorelbeke
A1 Jean-Marie Gorsbois
A1 Arnaud Scherpereel
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/1714.abstract
AB Introduction: patients with advanced or metastatic lung cancer (LC) or malignant pleural mesothelioma (MPM) have an alteration of quality of life (QoL) and physical capability induced by the cancer and (radio-)chemotherapy. Few studies assessed the value of pulmonary rehabilitation (PR) in this setting. We report the results of a prospective observational study on the feasibility and the safety of a PR program at home.Patients and Methods: 71 patients (60.6±8.8 years) treated by chemotherapy for LC (n=54) or MPM (n=17) benefited from a 6 or 8 weeks PR program (2 visits/week) combining electrostimulation or exercise training with therapeutic education and psycho-social help. Patients were assessed by exercise tolerance tests [6 minutes walk test (6MWT), 6 minutes stepper test (6ST), Time Up and Go (TUG), 10 times chair stand-up (10LC)] and QoL questionnaires (HAD, VSRQ).Results: there was no adverse event due to PR; 24 pts (34%) stopped PR early for personal reason (n=4), PS alteration (n=7), infection (n=3), excess of constraint (n=3), hospital admission (n=1) or cancer-related death (n=6). Patients assessment after PR showed stable value of 6MWT and improvement of 6ST (p=0.07), TUG (p=0.07) and 10LC (p=0.04) values. Daily physical activity (p=0.007) and anxiety (p=0.02) were significantly improved.Conclusion: As found in breast, colo-rectal or prostate cancers, we showed that a home PR program is feasible and well-tolerated in our LC or MPM patients. Moreover, patients benefiting from full PR program exhibited significant improvements in QoL and exercise tolerance. Full data including survival will be presented during the meeting.