PT  - JOURNAL ARTICLE
AU  - Alina Croitoru
AU  - Diana Ionita
AU  - Daniela Gologanu
AU  - Irina Pele
AU  - Stefan Dumitrache-Rujinski
AU  - Claudia Toma
AU  - Ionela Belaconi
AU  - Tudor Constantinescu
AU  - Daniela Jipa
AU  - Marius Duna
AU  - Miron Bogdan
TI  - Correlations between respiratory muscle strength, functional and non-functional parameters in COPD patients
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P4266
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P4266.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P4266.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Introduction: This study analyzed the respiratory muscle strength in a group of COPD patients and the possible relationship with other functional and non-functional parameters.Subjects and methods: In consecutives, stable COPD patients were evaluated: respiratory muscle strength (maximal inspiratory pressure MIP, maximal expiratory pressure MEP), lung function tests (FEV1, residual volume RV, functional residual capacity FRC), 6 minutes walking test (6MWT), modified Medical Research Council dyspnea scale (mMRC), COPD Assessment Test (CAT), St. George Respiratory Questionnaire (SGRQ), Hospital Anxiety and Depression Scale (HADS).Results: 70 COPD patients: 11 females / 59 males. Mean age 62.2±11 years. Mean MEP value: 125.4 ±40 cm H20. Mean MIP value: 67.5 ±23 cm H20. Both MIP and MEP values were correlated positively with: 6MWT distance, FEV1 values (p&amp;lt;0.05), and negatively with: dyspnea, age (p&amp;lt;0.05). MEP value was correlated with weight (p&amp;lt;0.05). No relationship was found with RV, FRC values or with CAT, SGRQ, HADS questionnaires. Concerning the MIP, the lowest values were in stage II GOLD (60.1 cm H20) and in 41.4% of cases the values were &amp;lt; 60 cm H20 (inspiratory muscle fatigue threshold).Conclusions: In our group of COPD patients, respiratory muscle pressures were in relationship with age, weight, dyspnea, FEV1 values and 6MWT distance. Inspiratory muscle pressure was seriously affected in almost half of patients.