%0 Journal Article %A Alina Croitoru %A Diana Ionita %A Daniela Gologanu %A Irina Pele %A Stefan Dumitrache-Rujinski %A Claudia Toma %A Ionela Belaconi %A Tudor Constantinescu %A Daniela Jipa %A Marius Duna %A Miron Bogdan %T Correlations between respiratory muscle strength, functional and non-functional parameters in COPD patients %D 2014 %J European Respiratory Journal %P P4266 %V 44 %N Suppl 58 %X Introduction: This study analyzed the respiratory muscle strength in a group of COPD patients and the possible relationship with other functional and non-functional parameters.Subjects and methods: In consecutives, stable COPD patients were evaluated: respiratory muscle strength (maximal inspiratory pressure MIP, maximal expiratory pressure MEP), lung function tests (FEV1, residual volume RV, functional residual capacity FRC), 6 minutes walking test (6MWT), modified Medical Research Council dyspnea scale (mMRC), COPD Assessment Test (CAT), St. George Respiratory Questionnaire (SGRQ), Hospital Anxiety and Depression Scale (HADS).Results: 70 COPD patients: 11 females / 59 males. Mean age 62.2±11 years. Mean MEP value: 125.4 ±40 cm H20. Mean MIP value: 67.5 ±23 cm H20. Both MIP and MEP values were correlated positively with: 6MWT distance, FEV1 values (p<0.05), and negatively with: dyspnea, age (p<0.05). MEP value was correlated with weight (p<0.05). No relationship was found with RV, FRC values or with CAT, SGRQ, HADS questionnaires. Concerning the MIP, the lowest values were in stage II GOLD (60.1 cm H20) and in 41.4% of cases the values were < 60 cm H20 (inspiratory muscle fatigue threshold).Conclusions: In our group of COPD patients, respiratory muscle pressures were in relationship with age, weight, dyspnea, FEV1 values and 6MWT distance. Inspiratory muscle pressure was seriously affected in almost half of patients. %U