RT Journal Article SR Electronic T1 Tear gas causes small airway obstruction in women JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4959 VO 44 IS Suppl 58 A1 Eda Uslu A1 Gulcihan Ozkan A1 Cagla Uyanusta Kucuk A1 Hilal Onaran A1 Cagla Pinar Tastan Uzunmehmetoglu A1 Aslihan Ilgaz A1 Gamze Ayar A1 Makbule Ozlem Akbay A1 Hikmet Firat A1 Tansu Ulukavak Ciftci A1 Serdar Akpinar A1 Bulent Ciftci A1 Selma Firat Guven A1 Selen Bilekli A1 Arif Muezzinoglu A1 Fatih Torlak A1 Peri Arbak A1 Elif Dagli YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P4959.abstract AB Objective: There is little known about effects of tear gas on different genders. This study was carried out to investigate the respiratory complaints and lung functions in women and men exposed to tear gas.Methods: During the June 2013 public demonstrations questionnaire survey was performed and lung function measuremenst were done in 460 demonstrators from Istanbul and 86 from Ankara.Findings: 283 males (age:31.2±11.1) and 262 females (aged:31.2±9.9) participated in the study. Smoking rates were found to be 62.3% in females, and 64.1 % among males. Females exposed to gas indoors were significantly higher than males 31.5 % vs 20.4 % p=0.015). Among females , compared to males chest tightness (79.4% vs 66.3%,p=0.001), cough (87.3% vs 77.8%, p=0.003), chest pain (51.7% vs 41.8%) , nasal discharge (78.8% vs 70.3%, p=0.016) and skin irritation (54.2% vs 40.8%, p=0.002) were significantly morefrequent. Duration of symptoms in males compared to females such as chest tightness (4.9 hrs vs 5.6 hrs), cough (6.0 hrs vs 7.0 hrs), sputum production (18.2 hrs vs 23.7 hrs) were significantly shorter (p >0.05). Lung function measurements showed %FVC of 99.0 % in females and 98.5 % males (p>0.05) ; FEV1 96.0 % in females and 101.5 % in males (p>0.05). FEV1/FVC were similar in both genders (102.4% vs 102.3However MMFR values in females were significantly lower than males (89.8 % vs 97.4 % p=0.005).Conclusion : Higher rates of respiratory symptoms and lower small airway funcitons in females may be due to exposure indoors. Neverthless the possibility of gender response variability must be researched.