TY - JOUR T1 - Effect of periodized aerobic training on power and autonomic modulation in COPD patients JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P605 AU - Marceli Leite AU - Ercy M.C. Ramos AU - Ana Paula Freire AU - Bruna S. Silva AU - Juliana Nicolino AU - Rafaella F. Xavier AU - Giovana N. Bertolini AU - Paula Pestana AU - Rafaela C. Cuissi AU - Renata David AU - Iara Buriola AU - Marcelo Papoti AU - Celso R.F. Carvalho AU - Luiz C.M. Vanderlei AU - Dionei Ramos Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P605.abstract N2 - Background: The most effective method of aerobic training in COPD is continuing under investigation. In healthy individuals, periodized aerobic training has been considered superior than traditional methods; however, its effect on COPD patients has not yet been elucidated. Aim: To evaluate the effect of periodized aerobic training on aerobic power and autonomic modulation in COPD patients. Methods: 16 COPD patients were included in the study and randomized to either periodized training (PTG; N=10) or control group (CG; N=6). Aerobic power (cardiopulmonary exercise testing) and autonomic function (heart rate variability) were assessed at baseline and after 12 weeks of training. Linear periodized aerobic training was conducted in 3 mesocycles with a 4 weeks duration each. Comparison between baseline and 12 weeks was performed using paired Student's t test or the Wilcoxon test, in case of non-normally distributed data. Results: After 12 weeks of periodized training, PTG presented a huge increase in peak oxygen consumption in either total (0.72±0.39 to 1.9±1L/min; P=0.01) or relative values (VO2peak, 9.4±4 to 27.2±16.8 ml/kg/min; P=0.01) and it was also observed an increase in the parasympathetic response (HF index, 62.3±46.8 to 113.2±62.1 ms; P=0.04). In addition, after training it was observed an increase in maximal speed reached during peakVO2 (5.5±1.2 to 6.3±1.3 km/h; P=0.006) in PTG. No significant difference for any outcome was observed in CG (P>0.05). Conclusion: Periodized aerobic training promoted enormous benefits on the aerobic capacity and autonomic modulation in patients with COPD. ER -