PT  - JOURNAL ARTICLE
AU  - Jessica Taytard
AU  - Raphaël Vialle
AU  - Michelle Mayer
AU  - Laurent Servais
AU  - Harriet Corvol
AU  - Annick Clement
AU  - Guillaume Aubertin
TI  - Beneficial effects of non-invasive positive pressure ventilation before vertebral arthrodesis in patients with Duchenne muscular dystrophy
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P2964
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P2964.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P2964.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Introduction: Vertebral surgery for Duchenne muscular dystrophy (DMD) patients remains a challenge. The objective of this study was to analyse the postoperative respiratory outcome, according to the use of preoperative non-invasive positive pressure ventilation (NPPV).Patients and Methods: Retrospective study including 13 DMD patients who benefited from a vertebral arthrodesis in a tertiary referral hospital between January 2010 and June 2013. Median age was 13 years old (11.6-16.2) at time of surgery. The surgery was a posterior arthrodesis without thoracotomy. We compared 2 groups of patients with or without preoperative NPPV: NPPV group (8 patients) and non NNPV group (5 patients). We studied preoperative and postoperative pulmonary function test and respiratory muscle strength in these 2 groups. We analysed two main parameters: durations of postoperative invasive ventilation (IV) and hospitalisation in intensive care unit (ICU).Results: In the NPPV and non NPPV group, median forced vital capacity was respectively of 37% (29-57%) and 50% (59-42%). Total lung capacity was respectively of 61 % (71-47%) and 68 % (80-49%). There was no statistical difference as for the two main parameters studied. But we showed in NPPV patients a tendency towards shorter postoperative IV (1 vs 2 days) and ICU stay (2 vs 3 days). One patient, who did not benefit from preoperative NPPV, had a postoperative pulmonary atelectasis.Conclusion: For DMD patients with severe scoliosis, preoperative NPPV tends to reduce both postoperative IV and ICU stay durations after the vertebral arthrodesis, even for patients with more severely altered pulmonary functions.