@article {ErskineP1214, author = {Odette Erskine and John Wheatley and Peter Middleton}, title = {Subjective sleep quality in adults with cystic fibrosis}, volume = {44}, number = {Suppl 58}, elocation-id = {P1214}, year = {2014}, publisher = {European Respiratory Society}, abstract = {IntroductionIn patients with varying degrees of severity of cystic fibrosis (CF) lung disease, disturbances of sleep may impact on sleep quality. There are currently limited studies evaluating objective sleep measures (using polysomnography (PSG)), together with subjective sleep quality (using questionnaires).AimThe aim of this study was to evaluate sleep abnormalities and their impact in subjects with mild to severe CF lung disease.MethodsIn-laboratory PSG and spirometry were recorded for CF subjects during a period of clinical stability. All PSGs were analysed and scored according to standard criteria (AASM). Questionnaires administered at the time of PSG included the Epworth Sleepiness Scale (ESS) and the Pittsburgh Sleep Quality Index (PSQI).ResultsTwenty subjects with CF were recruited (male=7;age=30.7{\textpm}8.2 (mean{\textpm}SD) years; and body mass index (BMI):22.0{\textpm}3.7 kg.m2). Baseline percent predicted FEV1 (\%predicted FEV1) was 47.7{\textpm}13.5 (range 21{\textendash}73\%). Although, ESS was normal at 5.1{\textpm}3.4 arbitrary units, the mean PSQI was 6.7{\textpm}3.1 with 60\% of subjects rating themselves {\textquotedblleft}poor sleepers{\textquotedblright} i.e. PSQI\>5. There was no significant correlation between \%predicted FEV1 and PSQI across all the disease severity types. The sleep efficiency was normal at 83.8{\textpm}9.9\%. Arousal index (AI) was normal at 16.7{\textpm}8.0 (mean{\textpm}IQR) events per hour. Respiratory disturbance index (RDI) was mildly elevated at 7.3{\textpm}4.2 (mean{\textpm}IQR) events per hour.ConclusionsIn these CF subjects, objective sleep efficiency and the AI were within normal limits. In addition, the RDI was mildly elevated indicating mild sleep disordered breathing, which may be a cause of reduced sleep quality. CF subjects were not excessively sleepy but reported reduced subjective sleep quality.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/44/Suppl_58/P1214}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }