TY - JOUR T1 - The impact of mixed etiology in community acquired pneumonia (CAP) JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - 4649 AU - Beatriz Montull AU - Rosario Menendez AU - Raul Mendez AU - Toni Torres AU - Soledad Reyes AU - Rafael Zalacain AU - Alberto Capelastegui AU - Javier Aspa AU - Luis Borderias AU - Juan Martin-Villasclaras AU - Salvador Bello AU - Inmaculada Alfageme AU - Felipe Rodriguez-de-Castro AU - Jordi Rello AU - Luis Molinos AU - Juan Ruiz-Manzano AU - NAC CALIDAD Group Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/4649.abstract N2 - Background: Community-acquired pneumonia may course as a severe infection with poor outcome. Mixed etiology pneumonia has been associated with worse prognosis and higher mortality.Objective: To characterize clinical presentation and prognosis of polimicrobial CAP.Methods: A prospective multicentric cohort study was performed in 13 hospitals.Results: 4070 patients were included and etiological diagnosis was reached in 1506 (37%). The causal microorganisms found are depicted in the graph.The most frequent association in mixed etiology was two bacteria (S. pneumoniae plus another (71.1%)). Initial severity measured by prognostic scales, sepsis criteria, radiological findings and requirement of ICU admission was higher in polimicrobial CAP. Mortality was significantly higher in that group.View this table:Polimicrobial CAP presentationConclusions: Mixed etiology CAP most common is caused by S. pneumoniae plus another bacteria (71.1%), courses with higher initial severity, more ICU requirement and poor outcome. ER -