%0 Journal Article %A Florian Kirsch %T A systematic review of cost-effectiveness and quality derived from models evaluating smoking cessation interventions in patients with COPD %D 2014 %J European Respiratory Journal %P 202 %V 44 %N Suppl 58 %X Introduction: COPD is a chronic condition with severe consequences causing annual societal costs of over €3,000 per patient in Germany. It is strongly related to smoking, 85% up to 90% of COPD deaths are caused by smoking. The only management strategy to slow down the progression of COPD and to reduce the frequency of exacerbations is to quit smoking.Aim: The aim of this systematic review is to evaluate the cost-effectiveness of smoking cessation interventions in patients with COPD and to assess the quality of the economic models.Methods: A systematic literature search was conducted on 28th October 2013. The databases Pubmed, Embase, Business Source Complete, EconLit and WISO were screened for economic models evaluating smoking cessation interventions in patients with COPD. Afterwards costs of included models were inflated and data were extracted. Differences in results were interpreted considering the model quality, which was evaluated with help of a quality appraisal by Philips et al. (2006).Results: Ten studies met the inclusion criteria and the results for the interventions range from cost savings to additional costs of €19,427 per QALY (quality adjusted life year). It is not clear whether highly intense smoking cessation interventions (intensive counselling plus pharmacotherapy) should be favoured over less intense smoking cessation interventions (e.g. minimal counselling). With regard to the quality of the models it can be said that new models seem to be of higher quality.Conclusion: Regarding these results, some countries should rethink the exclusion of smoking cessation interventions for COPD patients from reimbursement. %U