PT - JOURNAL ARTICLE AU - Antoaneta Manolova AU - Galya Tsolova AU - Krassimira Kostadinova AU - Toma Avramov AU - Maya Tafradjiiska AU - Anelia Koteva AU - Kristin Evstatieva TI - Parental smoking, asthma and asthma-like symptoms in preschool children from Bulgaria DP - 2014 Sep 01 TA - European Respiratory Journal PG - P1130 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P1130.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P1130.full SO - Eur Respir J2014 Sep 01; 44 AB - Exposure to second hand smoke (HSH) is a risk factor for asthma development and progression in childhood.Purpose: To study the impact of pre- and postnatal parental SHS on asthma and asthma-like symptoms in Bulgarian preschool children.Methods: The presented data are drown from a national cross-sectional study of SHS effect on respiratory health comprising data of 2922 children (1410 boys and 1469 girls) aged 3-6 years. A standardized and validated aptation of the questionnaire ATS-DLD-78-C (child component) and child medical records are used. Statistical analysis is performed by SPSS for Windows 15.0 is used.Results show that 15.4% of mothers and 30.3% of fathers smoke throughout pregnancy. Lifetime smoking is established in 45.7% of the fathers and 39.0% of the mothers. In logistic regression analysis, maternal smoking during pregnancy (OR=1.72, 95% CI 1.10-2.71) and postnatal household smoking (OR 2.14; 95% CI 1.35-3.37) are independent predictors of asthma in children. Maternal and paternal lifetime smoking predicts wheezing (respectively OR=2.35, CI 1.29-4.27 and OR=2.21, CI 1.43-3.41), and night cough (respectively OR=1.80, CI 1.04-3.22 and OR=1.64, CI 1.08-2.50). Pre- and postnatal maternal smoking is responsible for the attacks of breathlessness (respectively OR=1.85, CI 1.17-2.505 and OR=1.,54, CI 1.04-2.94). Eczema before the age of 1 year is related to lifetime maternal smoking OR=2,14, CI 1.11-2.02 and pollen/dust allergy to household smoking (OR=1.40, CI 1.16-1,66).Conclusion: Our results support the opinion that parental smoking, especially mothers' plays a substantial role in the development of asthma and asthma-like symptoms in preschool children.