PT  - JOURNAL ARTICLE
AU  - Joanna Shakespeare
AU  - Lynsey Archer
AU  - Robert Hastings
AU  - Felix Woodhead
AU  - Emma Helm
AU  - Rhian Hughes
AU  - David Parr
TI  - Relationship between the incremental shuttle walk test (ISWT) and full cardiopulmonary exercise testing (CPET) in patients with idiopathic interstitial pneumonia (IIP)
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P1263
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P1263.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P1263.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Introduction Idiopathic Pulmonary Fibrosis (IPF) is the most common subtype of IIP. Exercise tolerance in patients with IPF is limited by mechanics and gas exchange with FVC, TLCO and exercise desaturation predicting mortality(1)Aims ISWT predicts maximal oxygen uptake in some patient groups e.g. COPD, however there is limited evidence in IPF. Small studies have suggested that there is a significant correlation between walking distance (ISWT) and peak VO2.Methods We performed lung function, ISWT and full cardiopulmonary exercise testing (CPET) in 43 patients with a diagnosis of IIP (23 definite IPF, 20 not definite IPF ). Patients were grouped into those with a clinically significant desaturation on exercise (>4% fall and to <90%) - [sigDesat-] and those without - [nonsigDesat].Results There was no significant correlation between ISWT and peak VO2 (r = -0.442). NonsigDesat patients had better resting lung function than sigDesat patients, although there was no difference in ISWT or peak VO2.View this table:Demographics and PhysiologyConclusions Resting lung function predicts exercise desaturation better than gas exchange measures obtained during exercise.1 Am J Respir Crit Care Med Vol 183 pp788-824, 2011.