PT - JOURNAL ARTICLE AU - Paulo Lopes AU - Fatima Fradinho AU - Alexandra Catarino AU - Ana Lopes AU - Maria João Matos TI - Weight changes in patients with obstructive sleep apnoea syndrome (OSAS) before and after CPAP DP - 2014 Sep 01 TA - European Respiratory Journal PG - P4922 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P4922.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P4922.full SO - Eur Respir J2014 Sep 01; 44 AB - Background - Obesity is a strong risk factor for OSAS and weight loss can reduce apnea severity or even lead to resolution of OSAS in some patients. Whether treatment with CPAP can prevent body weight gain is controversialObjectives - Determine the weight changes in OSAS patients before and after CPAP treatment and the relation with other parameters measuredMethods - A retrospective analysis was performed on 472 consecutives OSAS patients treated with CPAP and followed at the Sleep Disorders Unit of Coimbra University Hospitals. BMI, OSAS severity, ESS, co-morbidities, compliance to CPAP were collected. The clinical evaluation and initial recommendations regarding weight loss and lifestyle changes were performed on a first appointment (T0), at the night of the polysomnographie (T1) and after CPAP therapy (T2)Results - The mean age was 61.8±10.7 yrs and 83.7% were males. The apnea/hypopnea index (AHI) was on average 38.1±22.8 (55.4% had AHI>30). At T1, 24.5% increased weight and 40.8% lost weight, with significant BMI decrease. At T2, 24.4% of the patients lost weight and 58.5% had a significant increase of weight and BMI. The ESS at T0 was 11.7±5.8 and decreased to 3.3±3.8 (p<0.001). CPAP adhesion was 89.5±15.2%. Patients with higher BMI were more likely to have more associated pathologies, which did not occur in relation to age or severity of AHI. Obese patients which presented higher ESS score showed a more significant improvement in ESSConclusions - Our data suggests that an active weight loss and lifestyle changes plan should be assumed. The regular CPAP use with OSAS control, in many patients, gives them a false idea of security and consequently abandoned initial recommendations.