@article {RobertP4496, author = {Ruby Stella Robert and Vishal Bansal and Pawan Gupta and S.K. Chhabra and Rajendra Prasad}, title = {Gait characteristics and energy expenditure during 6-minute walk test (6MWT) in phenotypes of COPD}, volume = {44}, number = {Suppl 58}, elocation-id = {P4496}, year = {2014}, publisher = {European Respiratory Society}, abstract = {Background: Gait characteristics and energy expenditure during the 6MWT are considered to be of prognostic significance in patients with COPD. Aims: To evaluate the differences in the gait characteristics and energy expenditure during the 6MWT in emphysema-predominant and non-emphysematous phenotypes of COPD. Method: 31 consecutive patients with COPD (GOLD Stage I- 3.2\%, II- 45\%, III- 25.8\%, IV- 25.8\%) were enrolled in the study and categorized on the basis of CT-thorax into the above phenotypes. Disease severity and quality of life were assessed using COPD Assessment Test (CAT) and St George{\textquoteright}s Respiratory Questionnaire (SGRQ). Step count, movement intensity and total energy expenditure (TEE) were measured in both the groups during 6MWT using a move monitor (Dynaport Minimod, McRobertsTM). Data was analyzed using unpaired t-test. Results: 18 patients were diagnosed as emphysema-predominant and remaining 13 patients characterized as non-emphysematous phenotypes. Both the groups were comparable in their age, gender distribution, body mass index (BMI), degree of obstruction (FEV1) and 6-minute walk distance (6MWD). CAT and SGRQ scores were significantly higher (p=0.047 \& p=0.016 respectively) in the emphysematous group as compared to the non-emphysematous group. Significantly higher TEE was recorded in the emphysematous group (p= 0.047) as compared to non-emphysematous group though the gait characteristics (step count and movement intensity) did not differ across the two groups. Conclusions: Emphysema-predominant phenotypes have higher energy expenditure during comparable walk distance and poor quality of life at similar degree of obstruction as compared to non-emphysematous phenotype.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/44/Suppl_58/P4496}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }