RT Journal Article
SR Electronic
T1 Cardiovascular profile in patients with COPD in rehabilitation program
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P614
VO 44
IS Suppl 58
A1 Daniel Omersa
A1 Nanca Cebron Lipovec
A1 Tatjana Kosten
A1 Mitja Lainscak
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P614.abstract
AB OBJECTIVE: COPD is associated with cardiovascular (CV) conditions, largely through shared risk factors and pathophysiology. For patients undergoing rehabilitation, CV profile is relevant for risk stratification and individual program tailoring. With limited data in the literature, we performed CV screening in patients referred for rehabilitation.METHODS: Detailed CV history, clinical investigation, echocardiography, electrocardiogram (ECG) and NT-proBNP were assessed in patients starting the rehabilitation between 2012 and 2014. Odds ratio (OR) for CV condition was assessed in multiple logistic regression analysis including age, sex, hypercholesterolemia (HCE), arterial hypertension (AH) and GOLD stage.RESULTS: Overall, 90 patients (66±8 years, 68% men, 84% GOLD III/IV) were analyzed. Known history of AH, ischemic heart disease, atrial fibrillation and HCE was present in 49%, 10%, 5% and 25% of patients, respectively. At least one CV condition was known in 19% and at least three in 1% of patients. Heart failure was known in 16% while additional 9% met European Society of Cardiology heart failure diagnosis criteria, mostly with preserved left ventricular ejection fraction. ECG heart rate was 86±15 beats/min; any ECG abnormality was observed in 21% of patients, with repolarization abnormalities (8%), widened QRS (7%) and right bundle branch block (6%) being most prevalent findings. NT-proBNP level >125 ng/l was recorded in 52%. Age (OR=1.18, p=0.006) and HCE (OR=30.27, p<0.001) was associated with significantly higher OR for CV conditions.CONCLUSIONS: CV conditions are prevalent in patients with COPD referred for rehabilitation. Detailed assessment increased the prevalence of heart failure.