PT - JOURNAL ARTICLE AU - Lesia Rasputina AU - Yuriy Mostovoy AU - Viktor Cherbak AU - Anna Rasputina AU - Hanna Demchuk AU - Irina Gncharova TI - Chronic obstructive pulmonary disease and myocardial infarction: Special aspects of clinical course in comorbid conditions DP - 2014 Sep 01 TA - European Respiratory Journal PG - P3616 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P3616.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P3616.full SO - Eur Respir J2014 Sep 01; 44 AB - A new edition of GOLD focuses on effect of concomitant cardiovascular diseases on the course of chronic obstructive pulmonary disease (COPD).The issue of exclusive clinical course of myocardial infarction (MI) in COPD patients is still poorly understood. We analyzed the course of MI in 31 patients with COPD, moderate COPD was diagnosed in 34.7% subjects and severe COPD in 65.3% subjects, mean age (56.7±4.3 ys) compared it with the data from the reference group - 35 patients, mean age (65.7±6.2 ys) with MI without history of COPD. We have learnt that 9 (29.4%) patients with COPD and MI were admitted to a hospital within 24 hours after start of pain syndrome, whilst the majority of patients without COPD (26 (75%)) within 12 hours. 47.1% of COPD patients demonstrated shortness of breath and asphyxia, while only 8.3% of patients had such symptoms in the reference group. Therefore, shortness of breath and asphyxia were taken for worsening COPD symptoms, thus leading to late medical care. At the same time all patients with COPD had more profound disorder. Q-MI infarction was diagnosed in 100% patients in this group and in 65% patients without COPD. The frequency of complications in patients with COPD was 76.5% and 45.7% in the reference group. The most frequent complications in the first group compared to the first one were: arrhythmia 69.2% and 51%, and conduction disorders - 30,8% and 12,1% accordingly. Therefore, comorbid COPD manifests shortness of breath and asphyxia that may lead to late medical help and significant increase in the frequency of complications of MI in this group of patients.