PT  - JOURNAL ARTICLE
AU  - Dmitriy Uryumtsev
AU  - Oleg Grishin
AU  - Viktor Grishin
TI  - Physiological effects associated with the use of respiratory devices
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P4269
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P4269.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P4269.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Background: The study of gas exchange and ventilation was previously carried out on a group of healthy subjects, where the response to the use of respiratory devices consisted of a decrease in respiratory rate, oxygen consumption, and carbon dioxide emission, as well as an increase in respiratory volume.Aim: To assess the impact of respiratory devices on ventilation and gas exchange parameters in patients with COPD.Methods: The study included patients with COPD (n= 21) of both sexes with the mean age of 59. The values of VE, f, Vt, VO2, VCO2, RER, VE/VO2 were recorded on a spirometabolic complex at the initial state and after connecting respiratory devices (Valve 22F-22V and Y - piece 22M, 22M/15F, Intersurgical). Each record was conducted successively over five minutes, while the subject was sitting ar rest and breathing ambient air.Results: It was found that the ventilation parameters did not significantly change during the study, while there was an 18% decrease in oxygen consumption (VO2) and 17% decrease in carbon dioxide elimination (VCO2); the ventilatory equivalent of oxygen (VE/VO2) increased by 15.5%, and the respiratory exchange ratio (RER) did not change.Conclusions: The observed decrease in gas exchange parameters is manifested in both healthy subjects and in patients with COPD. Yet, as opposed to healthy subjects, the patients with COPD show no changes in ventilation values. Thus, during the examination of patients, the impact of respiratory devices should be taken into account, which can vary depending on the respiratory system function.