PT  - JOURNAL ARTICLE
AU  - Yasemin Musteri Oltulu
AU  - Ender Coskunpinar
AU  - Engin Aynaci
AU  - Pinar Yildiz
AU  - Ilhan Yaylim
TI  - The value of miR221 and miR222 as a biomarker in non small cell lung cancer
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P510
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P510.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P510.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Aim of the study is investigate of expression levels of serum specific miRNA221 and miRNA222 as a biomarker in NSCLC.Thirty-two NSCLC cases and 30 healthy control cases that were diagnosed at Yedikule Chest Diseases and Chest Surgery, Training and Research Hospital were included in this study. In the study were used RT-PCR based miRNA (miR-qRT-PCR) detection methods. In NSCLC patients in accordance with control, miR221 and miR222 are expressed 1.46 and 1.63-fold, respectively, and while the difference of expression is statistically significant for miR221 (p:0.0001), significant difference did not be detected for miR222 (p:0.08)View this table:Table 1. The fold change of miR221 and miR222Keywords:NSCLC, biomarker, gene expression, miR221, miR222.