TY - JOUR T1 - The influence of malnutrition on pulmonary rehabilitation in patients with COPD JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P3036 AU - Sarah Jones AU - Samantha Kon AU - Jane Canavan AU - Claire Nolan AU - Melissa Ng AU - Amy Clark AU - William Man Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P3036.abstract N2 - Background Malnutrition impacts on exercise performance and health related quality of life (HRQOL) in COPD. Pulmonary rehabilitation (PR) is the cornerstone of management; however there are concerns that PR may exacerbate catabolic processes in malnutrition.Aims To determine the influence of malnutrition (measured by the Malnutrition Universal Screening Tool:MUST) on PR completion and response rates. To assess whether PR causes loss of weight or muscle mass in malnourished patients.Methods Completion rates were recorded in 1173 stable COPD patients referred to PR, stratified according to risk of malnutrition (MUST:0=low risk;>1=medium to high risk). Anthropometry, COPD Assessment Test (CAT), four metre-gait speed (4MGS), five-repetition sit-to-stand (5STS) and incremental shuttle walk (ISW) were measured pre and post an 8-week outpatient PR programme and Mann-Whitney U tests were used to compare change with PR between groups.Results PR completion rates were reduced in those with increased risk of malnutrition (MUST 0:completion 76.6% versus MUST>1:completion 64.6%,p=0.005). Table 1 summarises response to PR stratified to MUST score. There were small but significant increases in weight and fat free mass (FFM) with PR in MUST>1.Conclusion Those at increased risk of malnutrition have worse completion rates than those with low risk, but physical performance and HRQoL measures improve similarly. PR does not exacerbate catabolic process in patients with COPD at increased risk of malnutrition.View this table:Response to pulmonary rehabilitation ER -