PT - JOURNAL ARTICLE AU - Maria del Valle Somiedo Gutierrez AU - Virginia Pajares Ruiz AU - Jose Sanz Santos AU - Alfons Torrego Fernández AU - Felipe Andreo Garcia AU - Laura López AU - Jose Luis Mate AU - Justina Szafranska AU - Vicente Moral Plaza AU - Juan Ruiz Manzano TI - Diagnostic yield of endobronchial cryobiopsy in central tumours with previous non-diagnostic conventional forceps biopsy DP - 2014 Sep 01 TA - European Respiratory Journal PG - P703 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P703.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P703.full SO - Eur Respir J2014 Sep 01; 44 AB - AIM: Endobronchial cryobiopsy (EC) is a technique that obtains high quality specimens in patients with endobronchial tumours. The aim of our study was to evaluate the usefulness of EC in patients with a previous non-diagnostic sample obtained by means of conventional forceps biopsy (FB).PATIENTS AND METHODS:We included patients with an endobronchial tumour and a previous non-diagnostic conventional FB who underwent EC in two institutions from 2009 to 2013. Patients characteristics, sample adequacy, final diagnoses and procedure complication rate were analyzed.RESULTS:14 patients were included (10 men) with a mean age of 65.57 yrs (SD 13.4). All patients had a previous non-diagnostic bronchoscopy (range 1-3). EC attained a histological diagnosis in 13 patients (92.8%). Minimum complications were recorded: one case of pneumotorax and a moderate endobronchial bleeding. The mean specimen area of the biopsies obtained by EC was significantly larger than those obtained by FBView this table:Sample characteristics. The percentage of crush artefact was lower in biopsies obtainted by EC (difference statistically non-significant). The frozen of the sample did not interfere with the inmunohistochemical stainings or molecular techniques.CONCLUSIONS:EC obtained high quality samples that allowed histological diagnoses in most of the patients (92.8%) with a previous non-diagnostic FB. No fatal complications were recorded.