TY - JOUR T1 - Metabolic syndrome in patients with COPD admitted for exacerbation: Preliminary data JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P4103 AU - Evgeni Mekov AU - Yanina Slavova AU - Svetlana Hadjieva AU - Adelina Tsakova AU - Marianka Genova Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P4103.abstract N2 - Introduction: The Metabolic syndrome (MS) affects 21-53% of patients with COPD with a higher prevalence in the early stages of COPD, which is highly variable in different studies and subgroup examined.Aim: To examine the prevalence of MS and its correlation with comorbidities and disease characteristics of patients with COPD admitted for exacerbation.Methods: 92 patients were investigated for the presence of MS. All of them were also examined for diabetes mellitus (DM). Data were gathered for smoking status and exacerbations in the last year. The patients completed CAT and mMRC questionnaires and underwent spirometry.Results: 23,9% (n=22) of patients have MS. 76% (n=70) of patients are on therapy for arterial hypertension. 20% of the male and 31,3% of the female patients have MS (p>0,05). The presence of MS is associated with significantly worse cough and sleep (1st and 7th CAT questions; p=0.049 and p=0.015 respectively). Average BMI is 28,33. None of the patients had MS and BMI <25. MS tends to be more prevalent in younger patients (p=0.053). There is a tendency for a correlation between the presence of MS and DM (p=0.07) and with the number of exacerbations in the last year (p=0.16). There is no correlation between the presence of the MS and the pulmonary function. The prevalence of MS in this study is significantly lower when compared to a national representative study (30,8% in general population, over 50% in subjects over 60 years).Conclusions: This study finds relatively low prevalence of MS compared to previously published data (21-53%). Having in mind that MS is more common in the early stages and decreases with COPD progression, these patients may be considered as having advanced COPD. ER -