RT Journal Article SR Electronic T1 Exercise training associated with a weight-loss lifestyle program improves daily physical activity in obese asthmatics JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P3361 VO 44 IS Suppl 58 A1 Patricia D. Freitas A1 Palmira G. Ferreira A1 Aline G. Silva A1 Alberto Cukier A1 Regina C. Pinto A1 João M. Salge A1 Milton A. Martins A1 Marcio C. Mancini A1 Celso R.F. Carvalho YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P3361.abstract AB Background: Recent guidelines of pulmonary rehabilitation establish the importance of strategies to increase physical activity for patients with chronic respiratory diseases; however, such interventions in asthmatic patients, mainly in those obese have never been investigated. Aim: to assess the impact on daily life physical activity (DLPA) in obese asthmatics after an intervention aiming weight loss. Methods: 23 obese patients (BMI≥35kg/m2) with moderate or severe asthma were randomly assigned to either Control (CG=11) or Training (TG=12) group. Both groups performed an educational, nutritional and psychological program, twice a week for 3 months. TG performed exercise training, while the CG performed stretching exercises as placebo. Before and after the intervention, DLPA was measured using the accelerometer Actigraph and body composition by bioelectrical impedance. Outcomes were evaluated before and after intervention. Results: Before intervention, patients were sedentary (7,442±2,614 steps/day). After training, TG showed a significant increase in the DPLA (2,578±1,395 vs. 641±1,360 steps;p=0.018) as well as a reduction in percentage of body weight (7.1±3.2% vs. 2.7±2.9%;p=0.002) and in body fat (10.4±5.4% vs. 2.7±4.68%;p<0.001) compared to CG, respectively. TG group also reached the levels of physical activity for being considered active subjects (>10,000 steps/day). In addition, it was observed an association between weight loss and an increase in the daily number of steps (r=0.50;p=0.02). Conclusions: Our results suggest that exercise in a weight loss program is particularly helpful for obese asthmatics to lose weight and adopt a more active lifestyle.