TY - JOUR T1 - Compliance with non invasive home ventilation (NIHV) and its impact on survival: A retrospective descriptive study JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P459 AU - Simon Richards AU - Harman Saman AU - Marie Packer AU - Jodie Hunt AU - Syed Huq AU - Shyam Madathil Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P459.abstract N2 - Introduction: Despite the increasing use of NIHV in chronic hypercapnic respiratory failure, there is little data on compliance with its use and subsequent impact on survival.Methods: An observational single centre retrospective study of all patients commenced on HNIV between January 2002 and July 2013.Results: 90 patients were commenced on NIHV. Optimal compliance (as defined by NIV use for more than 6 hours/24 hours) varied according to underlying diagnosesView this table:Table1. Compliance was highest amongst patients with neuromuscular disease (100%) and lowest in those with COPD (48%). Suboptimal compliance was associated with higher mortality in all diagnoses but ORRF during the study periodDiscussion: Our data demonstrates that compliance with HNIV varies according to underlying diagnosis. For all diagnoses better compliance is associated with improved survival. The higher mortality despite optimal compliance in the ORRF group might be attributed to the complex co-morbidities usually associated with this condition. Future prospective studies are needed to examine this in detail and to identify factors associated with optimal compliance. ER -