PT - JOURNAL ARTICLE AU - Tomi Kovacevic AU - Bojan Zaric AU - Jelena Stanic AU - Branislav Sakic AU - Branislav Perin TI - Anxiety and depression in lung cancer patients - are there any relations to clinico-pathological characteristics? DP - 2014 Sep 01 TA - European Respiratory Journal PG - P2745 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P2745.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P2745.full SO - Eur Respir J2014 Sep 01; 44 AB - Introduction: Both anxiety and depression are present in significant number of patients with lung cancer. The primary aim of this trial was to evaluate frequency of anxiety and depression in investigated population. Secondary aim was investigation of correlation between clinico-pathological characteristics of lung cancer patients and anxiety disorder and/or depression.Patients and methods: This prospective observational trial was conducted at the specialized lung cancer university clinic. Seventy five inpatients with lung cancer diagnosis at various stages of treatment rated themselves on the Hospital Anxiety and Depression Scale (HADS). Clinico-pathological characteristics among others included Eastern Cooperative Oncology Group Performance Status (ECOG PS), and time from diagnosis. Univariate and multivariate analysis was performed in order to correlate the data.Results: Of total 75 patients enrolled 73.3%(55/75) were male and 26.7%(75/20) female. HADS-defined depression was identified in 29.3%(22/75) and anxiety in 22.7%(17/75). Most common lung cancer type was adenocarcinoma (52.0%) followed by squamous (30.7%) and small-cell lung cancer (17.3%). Average time from diagnosis was 10 months. Majority of patient 82.7%(62/75) had ECOG PS 1. There was significant correlation between anxiety disorder and ECOG PS (p=0.049).Conclusions: Anxiety and depression are diagnosed in significant number of lung cancer patients. With exception of ECOG PS we did not observe significant correlation between characteristics and anxiety disorder and/or depression, however we believe that further studies with larger number of subjects are needed to confirm these results.