PT - JOURNAL ARTICLE AU - Daniel Swamydass AU - Rachel Roberts AU - James Barry AU - Eiry Edmunds AU - Mark Andersen AU - Chris Warren AU - Keir Lewis TI - Night to night variability in sleep breathing pattern in people awaiting biventricular pacemaker for severe heart failure DP - 2014 Sep 01 TA - European Respiratory Journal PG - P2254 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P2254.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P2254.full SO - Eur Respir J2014 Sep 01; 44 AB - INTRODUCTIONThe prevalence of sleep disordered breathing in people with left ventricular failure has been reported at 40-60%1.We wanted to look at night to night variations in sleep disordered breathing in a cohort of patients referred for biventricular pacemaker for heart failure (HF) according to national guidelines. 2METHODSProspective, Observational study.24 patients (19 males), with NYHA category 3-4, mean (SD) Left Ventricular Ejection Fraction =25 (7)%, QRS duration > 120 msec on ECG; all were deemed on optimal medical treatment for their HF by a Cardiologist. They had limited channel sleep studies (Apnea LinkTM ResMed, Abingdon, UK) for two consecutive nights, 7 days prior to elective implant biventricular pacemaker at a UK tertiary center. We compared the 2 sleep studies in all patients.RESULTSView this table:Night 1 versus Night 2, AHI correlation: Spearman's rho =0.745, p=0.001Cronbach's Alpha=0.84 for repeatability.CONCLUSIONThere is no significant variation over two consecutive nights in sleep breathing patterns in those with severe HF who awaiting biventricular pacemaker. We recommend that one night of sleep study is reliable to diagnose sleep disordered breathing in patients with severe HF.REFERENCES1. Eur.Resp.J.2007.Jun:29(6)1201-52. www.nice.org.uk/TA120.