RT Journal Article
SR Electronic
T1 Tuberculosis (TB) and young age
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2654
VO 44
IS Suppl 58
A1 Maria Korzeniewska-Kosela
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P2654.abstract
AB Aim: Comparison of TB features in children, adolescents and young adults.Method: Data from TB Register were analyzed. Statistical significance (Si) was assessed with chi2 test.Results: In total (IT) 10.1807 TB cases were notified from 2002 to 2013 in Poland including 341 cases below 5year of life (A); 313 aged 6 to 10 yrs (B), 654 aged 11 to 15 yrs (C); 2168 aged 16 to 20 yrs (D) and 3784 aged 21 to 25 yrs (E).Pulmonary TB as the sole (91.5 % IT) was in similar proportion in A and B (35.2% and 33.5%). With age proportion rose to 88.6 % (Si). Pulmonary TB was culture confirmed (IT 63.7%) in 36.3% of A; 29.8 % of B; 50.7 % of C; 65.2% of D; 68.9 % of E (Si, except AvB). Smears were positive (IT 39,4%) in 17.4 % of A; 10.8 % of B; 19.3 % of C; 40.4 % of D(Si); 45.0 % of E (Si).Solely extrapulmonary TB (IT 7.8%) occurred in 60.4 % of A; 63.6 % of B; 42.7% of C; 10.9% of D; 8.2% of E (Si, except AvB). Miliary TB was most often in B (2.2%); TB meningitis in A (2.6%). Isoniazid resistance and MDR-TB were most often in C (8.8% and 3.5%; IT 3.1 and 0.7%). Pleural TB (IT 3.2%) was in 2.0% of A; 6.7 % of B (Si); 7.6 % of C; 5.8% of D; 4.9 % of E.Occurrence ofchest lymph nodes TB (IT-0,6%) decreased in consecutive groups from 42 % to 0.2%)(Si, except AvB).In all groups except C, there were more males, most in E (54,8%) (67% in IT).Defaulters (IT 8,8%) were 3.4 % in A; 2.4 % in B; 3.9 % in C; 5.3 % in D; 6.7% in E (Si).Conclusion: Extrapulmonary TB predominates in children up to10 yrs. With age pulmonary TB continues to emerge. Young aged 21 to 25 yrs as the first have the TB characteristics similar to whole population of patients. Teenagers and young adults require concern because infectious TB, drug resistance and default are common in these groups.