PT - JOURNAL ARTICLE AU - Siraj Wali AU - Abeer AlKhouli AU - Mohannad Howladar AU - Saad Alshuhaib AU - Ibrahim Ahmad AU - Saeed Alghamdi AU - Ayman Krayem TI - Obstructive sleep apnea among patients with chronic renal failure on regular hemodialysis in Saudi Arabia DP - 2014 Sep 01 TA - European Respiratory Journal PG - P2270 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P2270.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P2270.full SO - Eur Respir J2014 Sep 01; 44 AB - IntroductionIn Chronic Renal Failure patients (CRF), sleep apnea may worsen and clinical symptoms and aggravate the cardiovascular complications of end-stage renal disease (ESRD). Sleep apnea was reported to be in more than half of ESRD patients, while it was reported to range from 5 to 20 percent in the general population. Locally, there is only a single report on the prevalence of OSA in Saudi ESRD patients.AimThe aim of this study is to investigate the prevalence of OSA in patients with chronic renal failure on hemodialysis (HD) in multiple centers.MethodsThis cross-sectional study was carried out in three dialysis centers in Jeddah, Saudi Arabia, from June 2012 to September 2013. OSA was assessed using Berlin questionnaire and Epworth Sleepiness Scale (ESS) was used to asses excessive daytime sleepiness. In addition, detailed information about medical, clinical and laboratory results were also obtained.ResultsAmong 355 enrolled patients, the mean patient age was 45.5 years ± 15.4 years; 61% were male. The overall prevalence of OSA as defined by Berlin questionnaire was 46.3%. Prevalence was 47% in males and 44% in females, (P: 0.658). The prevalence of excessive daytime sleepiness was (74%). Sleep apnea was significantly associated with diabetes mellitus, hypertension, and hepatitis C (P-values: 0.01, < 0.0001, and < 0.003, respectively). Sleep apnea was also significantly associated with excessive daytime sleepiness (P-values: < 0.0001).ConclusionOSA is quite more common in the ESRD patients than in the general population and affects both genders equally. Interestingly, there is significant association of OSA with hepatitis C that would need further confirmation.