RT Journal Article SR Electronic T1 Effect of the use of electronic cigarettes (e-Cig) in smoking asthmatics (SA): A retrospective evaluation JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 3440 VO 44 IS Suppl 58 A1 Riccardo Polosa A1 Pasquale Caponnetto A1 Massimo Caruso A1 Simona Strano A1 Cristina Russo A1 Jaymin Morjaria YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/3440.abstract AB BackgroundSA have frequent exacerbations, poor health status and disease control. E-Cigs are an alternative smoking strategy to conventional cigarettes.AimTo evaluate the effects of e-Cigs as an alternative to tobacco use in SA.MethodsWe retrospectively reviewed changes in lung function, methacholine airway hyperresponsiveness and asthma control in SA who had been using e-Cigs for at least 12 months. Measurements were taken prior to use, at 6 and 12 months.Results18 SA were identified with a mean age of 39 (±12) and smoking pack years of 21 (±10); 10 single (e-Cig only) and 8 dual users (e-Cig and conventional cigarettes ≤4cig/day). The findings are summarised below.View this table:Parameter measurements at baseline (BL), 6- and 12-months (M)No adverse events were reported.ConclusionsE-Cig use appears to have beneficial effects on respiratory physiology and subjective asthma outcomes, suggesting that these products may be a valid and safe option for SA not intending or unable to quit tobacco use. Larger controlled studies are required to substantiate our findings.