RT Journal Article SR Electronic T1 Cardiac output by direct Fick, thermodilution and modelflow in pre-capillary pulmonary hypertension JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2379 VO 44 IS Suppl 58 A1 Frédéric Lador A1 Gilles Garcia A1 Aurélien Bringard A1 Guido Ferretti A1 Paola M. Soccal A1 Gérald Simonneau A1 Philippe Hervé A1 Olivier Sitbon YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P2379.abstract AB BackgroundThe direct Fick (dF) is the reference method for cardiac output (CO) measurements but Thermodilution (TD) is widely used in pre-capillary PH (pcPH) evaluation.AimTo compare, CO from dF (COFick), TD (COTD) and the Modelflow method applied to non-invasive pulse pressure profiles (COMF) .MethodsWe determined CO in pcPH patients at rest. COTD as the mean of 3 values, COMF of 100 beat-by-beat values, and COFick simultaneously.ResultsPatients characteristics are in the table. The figure shows (A) COMF against COFick (B) COMF - COFick against their mean (Bias: 0.7; Limits of agreement (LoA): -1.08/+2.48). (C) COTD against COFick . (D) COTD - COFick against their mean (Bias: -0.20; LoA: -2.55/+2.15).View this table:Characteristics of the study populationConclusionMF showed better correlation and precision than TD when compared to dF. Calibration with a reference method is needed to improve accuracy.