TY - JOUR T1 - Pesticides environmental exposure and respiratory health in schoolchildren JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1947 AU - Ali Mamane AU - Emilie Berteaud AU - Ghislaine Bouvier AU - Isabelle Baldi AU - Chantal Raherison Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1947.abstract N2 - Exposure to environmental factors may contribute to respiratory symptoms, in vulnerable subjects particularly children. In rural area, children's pesticides exposure included usually residential proximity to farmland, and domestic exposure.A pilot study was performed in rural area in south-west of France to evaluate the impact of pesticides used in vineyards culture, on respiratory health in schoolchildren during pesticides-treatment. Three hundred and ten schoolchildren were included in this study, (Means age [3-11 years old]). Parents answered a standardized questionnaire (ISAAC ) on respiratory symptoms and domestic pesticides use. Air Pesticides exposure at schools was measured by monitors in classrooms.24.8% of children had ever wheeze, 29.1% had cough episodes during past year, and 17.6 % had asthma. 36.2% had rhinitis and 32.2% had rhino-conjunctivitis during past year. Three major pesticides were identified in schools : Folpel, CS2 and chlorpyriphos methyl. Children highly exposed to Folpel, had significantly more rhinoconjunctivitis (OR: 3.26 [1.14-9.29). Children highly exposed to CS2 had a higher risk of allergic conjunctivitis (OR: 3.04 [1.31-7.04]). Insecticide domestic use was associated with rhinitis (OR: 1.82 [0.99-3.5]). Lice killer lotion was associated with current rhinitis (OR: (3.56[0.99-12.59]), dyspnea episodes (OR: 3.84[1.18-12.46]) and allergic cough (OR: 2.12 [1.07-4.2). Any domestic pesticide exposure was associated with current rhinitis (OR: 3.67[1.47-9.1]) and allergic cough (OR: 2.37[1.08-5.1]).Pesticides exposure had a significant impact for children in schools located near pesticides-treated lands.Fundings : Fondation du souffle, ANSES. ER -