RT Journal Article
SR Electronic
T1 Is systematic polygraphy necessary during long-term continuous positive airway pressure (nCPAP) in children?
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4714
VO 44
IS Suppl 58
A1 Alessandro Amaddeo
A1 Valeria Caldarelli
A1 Marta Fernandez-Bolanos
A1 Johan Moreau
A1 Sonia Khirani
A1 Brigitte Fauroux
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P4714.abstract
AB Introduction: The persistence of respiratory events during nCPAP in children has not been studied. The present study aims to describe respiratory events during nCPAP and to determine their clinical consequences.Materials and Methods: 31 nocturnal polygraphic (PG) recordings were performed in 27 stable patients under nCPAP (7 female, mean 7.3±5.9 years), without any clinical symptom of persistent sleep disordered-breathing (SDB). PGs were scored using SomnoNIV Group definitions. For every event, the presence of a desaturation (≥3% fall of pulse oximetry (SpO2)) or a respiratory related autonomic micro-arousal (RAM), defined as ≥30% decrease in pulse wave amplitude, was systematically searched.Results: Nocturnal mean nocturnal SpO2, overnight transcutaneous carbon dioxide tension (PtcCO2) and desaturation index were 97±1%; 41±5 mmHg and 3±4 respectively. Mean % of time spent with PtcCO2 >50mmHg was 4±14%. Mean index of event per hour for unintentional leaks, partial or total upper airway obstruction ± reduction of ventilatory drive, decreased ventilatory drive, and mixed events was 0.3; 0.6; 1.6; 0.2 and 0.05 respectively. These events were associated with a desaturation in 19%, 29%, 48%, 25% and 6% and with a RAM, in 22%, 13%, 48%, 25% and 6% of patients respectively. The mean percentage of total time spent with an event was 7±10%. A predominant event was always identified and represented 80±24% of total time spent with respiratory events.Conclusion: Respiratory events are rare during nCPAP in children without residual symptoms of SDB. Further studies are necessary to determine the optimal timing of PG during nCPAP in children.