PT - JOURNAL ARTICLE AU - Karen Ingram AU - Jane Canavan AU - Samantha Kon AU - Claire Nolan AU - Sarah Jones AU - Amy Clark AU - Djeya Kaliaraju AU - William Man TI - Repeat pulmonary rehabilitation programmes: Are they beneficial in COPD? DP - 2014 Sep 01 TA - European Respiratory Journal PG - P610 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P610.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P610.full SO - Eur Respir J2014 Sep 01; 44 AB - Recent guidelines indicate that repeat PR should be offered to patients who have completed a course more than one year previously and remain functionally limited. However this is based on a paucity of data and it is not known whether patients who failed to gain benefit from their original PR course improve with repeated PR.125 patients with COPD completed two separate PR courses at least 1 year apart from Sept 2009-Aug 2013. The Chronic Respiratory Questionnaire (CRQ) and Incremental Shuttle Walk (ISW) were measured pre and post course 1 (PR1) and 2 (PR2). The response to PR within, and between, PR1 and PR2 was assessed using paired t-tests. Subgroup analysis included patients who did not benefit from PR1 (ISW<47.5m, CRQ total <10 point improvement). Data are presented as mean and standard deviation (SD) or mean difference (95%CI).Mean duration from the end of PR 1 to PR 2 was 555 (268) days, with FEV1% stable over time (0.92 (-1.2 to 3.0) p=0.39). There was a statistically significant improvement in ISW and CRQ with PR1 (64 (50 to 77)m;16.4 (19.9 to 12.9)) and PR2 (46 (36 to 56)m; 11.1 (8.0 to 14.2)) - all p<0.0001. Comparison of the response to PR1 and PR2 identified a statistically but not clinically significant difference for ISW change (PR1 versus PR2: 17.5 (2.3 to 32.7)m; p=0.025) and CRQ total (5.3 (0.92 to 9.6) p=0.02). In those who did not benefit from PR1, 63% showed an improvement in ISW or CRQ with PR2.Patients with COPD significantly improve health related quality of life and exercise capacity with repeat PR, but response is heterogeneous. A significant proportion of patients who show no benefit with initial PR showed improvement in either exercise capacity or health status with repeated PR.