RT Journal Article SR Electronic T1 Evaluation of the use of CAT in COPD. Results of On-Sint study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4020 VO 44 IS Suppl 58 A1 Cecilia López Ramírez A1 Lucía Marín Barrera A1 José Luis López- Campos A1 Carmen Calero Acuña A1 Alberto Fernández Villar A1 Cristina Represas Represas A1 Cecilia Mouronte Roibas A1 Ricard Casamor Casamor YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P4020.abstract AB Introduction:The On-Sint, is a retrospective cohort study that aims to evaluate the clinical and functional presentation of chronic obstructive pulmonary disease (COPD) at the moment of diagnosis and its progression in time, both in primary (PC) and Specialized (SC) care.This paper shows the results of the use of COPD Assessment Test (CAT) in this cohort.Method:Observational non-intervention study to generate a retrospective cohort in which 329 primary care physicians or pulmonologists from Spain included 1214 smokers or former smokers diagnosed with COPD. The information in our cohort was collected in two different periods, at the time of diagnosis and at present. All patients completed the CAT at present and its possible relation with different clinical variables was analyzed.Results:The On-Sint cohort consists of 1214 COPD patients (78.7% men , 70.6% of PC , age 66.4±9.7 years, 54.8% smoking at diagnosis , body mass index 27.7±4.1 kg/m2). CAT´s total score was 18.3±7.6, with significant differences (p < 0.001) between PC (19.2±7.3) and SC (16.2±7.9) with no differences according to smoking status. CAT score was progressively associated with the three axes of GOLD: lung function (GOLD1 15.2±7.3; GOLD4 19.7±8.1, p<0.001), number of exacerbations (0-1 exacerbations: 15.0±7.1 vs ≥ 2: 20.1±7.2, p<0.001) and dyspnea (mMRC 0 13.1±7.8 vs mMRC 4 26.1±8.9, p<0.001) Besides, we also found a clear progressive relationship between the number of comorbidities and the CAT score (15.2±6.8 without comorbidities and 29.3±9.8 with 7 comorbidities, p<0.001).Conclusions:Although CAT is relatively recent, it seems to reflect well at least some of the complexity of COPD, helping us to measure the impact of the disease.