PT  - JOURNAL ARTICLE
AU  - E.B. Klester
AU  - L.A. Plinokosova
AU  - Ya.N. Shoichet
AU  - K.V. Klester
AU  - O.A. Ivanov
TI  - Peculiarities of intracardiac hemodynamics in patients with chronic obstructive pulmonary disease
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P3583
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P3583.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P3583.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Objective: To evaluate systolic and diastolic function of the LV and RV myocardium, pulmonary hemodynamics in patients with COPD.Material and methods: The study involved 211 patients with mild and moderate COPD in remission who were in the 70-bed capacity therapeutic department in hospital No. 4 for the period 2012-2013 years. Among the surveyed were 147 men and 64 women aged 60 to 90 years. COPD is diagnosed in accordance to recommendations GOLD (2011), the duration of COPD is 21,8 ± 5,3 years.Results: All patients with COPD were revealed disturbances as a of RV diastolic dysfunction (E / A TV= 0,95 ± 0,13) and LV (E / A MV = 1,01 ± 0,22), which confirms the presence of heart failure. A clear trend towards worsening of RV dysfunction was traced in patients with moderate severity of COPD. This was manifested by appearance in these groups patients with restrictive type of transtricuspid flow. RV hypertrophy has evolved with moderate COPD (RV wall thickness= 5,21 ± 1,01 mm, (E / A TV = 0,91 ± 0,21), with the progression of diastolic dysfunction (E / A MV = 0,94 ± 0.17). Pulmonary hypertension in patients with COPD is medium, with mild COPD MPAP was 20,34 ± 2,45 mmHg, with moderate - 22,21 ± 1,67 mm Hg. LVMI and left ventricular mass were significantly higher in moderate severity on 14.65% (p <0.01). The average value dimensions at LA with mild severity - 40,7 ± 0,89 mm, with moderate - 41,4 ± 2, 63 mm.Thus, in COPD patients even at mild degree diastolic LV and RV dysfunction, low pulmonary hypertension develops. Further progression of hemodynamic disturbances depends on the degree of reduction of respiratory function.