TY - JOUR T1 - Successful lung volume reduction improves inspiratory paradoxical movement of the lower rib cage at rest as measured by optoelectronic plethysmography JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P3718 AU - Zaid Zoumot AU - Antonella Lo Maoro AU - Andrea Aliverti AU - Christopher Nelson AU - Simon Ward AU - Simon Jordan AU - Claire Davey AU - Will McNulty AU - Michael Polkey AU - Pallav Shah AU - Nicholas Hopkinson Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P3718.abstract N2 - INTRODUCTION:Whether lung volume reduction(LVR) in patients with severe COPD improves inspiratory paradoxical chest wall movements has not been studied using 3-dimentional volume measurements of the chest wall. Optoelectronic plethysmography(OEP) allows breath by breath volume analysis of 6 chest wall compartments; left and right of each of pulmonary rib cage(Vrc,p), abdominal rib cage(Vrc,a) and abdomen(Vab).METHODS: 26 patients had OEP assessments during quiet breathing before and 3 months after LVR(LVR group (surgical n=9, bronchoscopic n=7)), or a sham bronchoscopy (control group, n=10). The phase shift angles were calculated for the asynchrony between Vrc,p and Vrc,a (θRC), and between Vrc,a and Vab (θDIA).RESULTS:At baseline, patients had severe airways obstruction(FEV<sub style="font-family: Calibri;">1 35(18)%pred) and hyperinflation(RV 218(42)%pred) and the groups were well matched. Between group difference in the change in θRC and θDIA was statistically significant in the direction of 0°(representing complete synchrony) favouring the LVR groupView this table:Difference in the change in Phase shift angle(Θ) during quiet breathing at 3 months.CONCLUSION:Successful LVR significantly improves chest wall asynchrony in patients with severe COPD. ER -