TY - JOUR T1 - Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P4313 AU - Henrik Johansson AU - Katarina Norlander AU - Christer Jansson AU - Andrei Malinovschi AU - Lennart Nordvall AU - Leif Nordang AU - Margareta Emtner Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P4313.abstract N2 - Introduction: Exercise can provoke transient narrowing of the airways as seen in exercise-induced bronchoconstriction (EIB). Exercise-induced laryngeal obstruction (EILO) comprising conditions involving vocal cords and/or supraglottic structures where airflow in larynx is hampered can also occur during physical exertion. Prevalence of EILO in a general population of adolescents, and its relation to exercise-induced bronchoconstriction (EIB), has not been previously investigated.Aim: To investigate prevalence of EIB and EILO, with standardized exercise tests, in a general adolescent population.Method: A questionnaire on exercise-induced dyspnea was sent to all adolescents born 1997-98 living in Uppsala, Sweden (n=3838). A randomized subsample of 146 adolescents were exercise tested (99 with self-reported exercise-induced dyspnea, 47 without). EIB-test was performed on treadmill while breathing dry air. A positive test was defined as a fall ≥10% in FEV1. EILO-test was performed on treadmill with filming of larynx and obstruction was graded according to criteria (Maat et al Eur Arch Otorhin 2009). Estimated prevalence for the whole population was calculated according to the theory for stratified samples.Results: The prevalence of EIB was 19.2% and the prevalence of EILO was 5.7% with no gender differences. In the group with exercise induced dyspnea 39.8% had EIB, 6% had EILO and 4.8% had both EIB and EILO.Conclusion: Though not as common as EIB, EILO is not uncommon in a general population and can be an important differential diagnosis in adolescents with exercise-induced dyspnea. EILO is equally common among girls and boys and can coexist with EIB. ER -