RT Journal Article
SR Electronic
T1 Diaphragmatic dysfunction in interstitial lung disease: An ultrasonography study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3539
VO 44
IS Suppl 58
A1 Pauliane Vieira Santana
A1 Elena Prina
A1 Renata Pletsch
A1 Jeferson Ferreira
A1 Mayra Caleffi Pereira
A1 Andre Apanavicius
A1 Patricia Trevisan
A1 Andre P. Albuquerque
A1 Carlos Roberto R. Carvalho
A1 Pedro Caruso
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P3539.abstract
AB Background: using non-volitional tests, respiratory muscle dysfunction has recently been implicated in exercise limitation in patients with interstitial lung disease (ILD). However ultrasound (US) evaluation of diaphragm has not been already described in these patients. Aims: In ILD patients, we evaluated the diaphragm with US and correlated these findings with pulmonary functional tests. Methods: In ten ILD patients, we performed US of the right diaphragm to evaluate mobility during quiet breathing (QB) and deep breathing (DB) and thickness at functional residual capacity (FRC) and at total lung capacity (TLC). We compared these results with 12 healthy volunteers. All patients performed spirometry. Results: The mean age of the patients was 58 years (±15 SD) and the mean forced vital capacity (FVC) was 57.4±18% of the predicted. In ILD patients, the motion of right diaphragm during DB is decreased when compared to volunteers (4.4±1,87 cm vs 7.48±0.81 p<0.001). The mobility strongly correlated with the FVC (R=0.86, p=0.001, fig1). At the FRC, the diaphragmatic thickness of patients was higher than volunteers (0.19±0.02 cm vs 0.16±0.03 p=0.048) but from FRC to TLC, the diaphragm of patients thickened lesser than volunteers (11.5% vs 21.7% p=0.014). Conclusions: In patients with ILD, the diaphragmatic mobility is reduced during deep breathing and this reduction is strongly correlated with the pulmonary volume.