RT Journal Article
SR Electronic
T1 Predictive radiological factors of delayed smear conversion
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2686
VO 44
IS Suppl 58
A1 Safa Hafaied
A1 Hajer Racil
A1 H. Blibech
A1 Sawsan Bacha
A1 Sana Cheikh Rouhou
A1 Nawel Chaouech
A1 Abdellatif Chabbou
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P2686.abstract
AB Introduction: Radiological lesions in pulmonary tuberculosis are polymorph. Some studies suggested that chest X-ray could predict patients with delayed sputum smear conversion and so higher risk of unfavorable evolution.The aim is to identify radiological factors associated to delayed sputum smear conversion.Materials: A retrospective case-control study was performed, compared chest X-ray of 100patients with confirmed pulmonary tuberculosis: 50 with delayed smear conversion (group A: GA) and 50 showed no delay (group B: GB).Results: Nodules were noted in both groups with no significant difference (98% vs 94%, p = 0.617), infiltrates were more noted in GB (80% vs 88%, p=0.275). Excavations were present comparably in both groups (92% vs 86%, p = 0.338). Although excavation's number was more important in GA, 68% of patient in GA had more than 4 excavations vs 24 % in GB (p <0.000). High cavitary score is also more frequent in GA (62% vs 24%, p = 0.00).Bilateral radiological lesions were more frequent in GA (74 % vs 56%, p=0.059).Severity of chest X-ray lesion evaluated by the BIT score was higher in GA with an average at 10.22 ± 0.739 in GA vs 7.92 ± 0.604 in GB; p = 0.018.Conclusion: Patients with extensive radiologic lesion and multiple cavitary should have a specific attention to guarantee a favorable evolutionand to reduce the risk of relapse or treatment resistance.