PT - JOURNAL ARTICLE AU - Lurdes Planas AU - Yolanda Ruiz AU - Nuria Gonzalez AU - Ana Cordoba AU - Eva Farrero AU - Jordi Dorca AU - Enric Prats TI - Transcutaneous carbon dioxide monitoring in patients with acute respiratory failure DP - 2014 Sep 01 TA - European Respiratory Journal PG - P2087 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P2087.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P2087.full SO - Eur Respir J2014 Sep 01; 44 AB - Transcutaneous carbon dioxide (PtcCO2) monitoring is a non-invasive method increasingly being used to assess acute respiratory failure (ARF).However there are conflicting findings when evaluating high levels of PaCO2.The aim of our study is to evaluate the accuracy of this method in ARF patients according to the severity of hypercapnia.Method: prospective study including patients with ARF admitted in a RICU, who required arterial blood gas (ABG) analysis. Simultaneously, PtcCO2 was measured (SenTec digital monitor). Data: patients demographics, diagnosis, ABG and PtcCO2. Data are presented as mean ± SD. Relations between PaCO2 and PtcCO2 were assessed by Pearson correlation coefficient and the intraclass correlation coefficient (ICC). Bland-Altman analysis was used to test data dispersion. ANOVA test was used for comparing the difference of PaCO2 and PtcCO2, in different levels of PaCO2: level 1 <50 mmHg, level 2 50-60 mmHg, level 3 >60 mmHg.Results: 74 patients, mean age 66 ± 11 years. Most frequent diagnosis was AECOPD (40%). Mean PaCO2 was 58 ± 11 and mean PtcCO2 was 54 ± 10 mmHg. Correlations between PaCO2 and PtcCO2 was r =0,92 (p<0,001) and the ICC was 0,92(p<0,001). The mean difference between PaCO2 and PtcCO2 was 4,5 ± 4,3 and the limits of agreement (bias ± 1,96 SD) ranged from -3,9 to 13 (Bland-Altman analysis). Difference between both variables increase as the same time as PaCO2 severity: level 1=1,7 ± 3,2;level 2 =3,6 ± 2,8; level 3=6,5 ± 4,9 (ANOVA test p<0,0001).Conclusions: our study showed good agreement of PtcCO2 monitoring with ABG. However, we have to take into account two aspects: PtcCO2 undervalues PaCO2 levels and PtcCO2 is less reliable in patients with sever hypercapnia.