TY - JOUR T1 - The frequency of antimicrobial prescriptions against airway's infections during pregnancy JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1056 AU - Roman Bontsevich AU - Oleg Golovchenko AU - Zhanna Chefranova AU - Mikhail Pokrovsky AU - Tatyana Pokrovskaia Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1056.abstract N2 - The aim of work was to study the frequency of antimicrobial prescriptions (AP) against airway's infections (AI) in pregnant women.Material and methods.We have been registering the cases of AP in pregnant women against AI during specialized advisory attendances held in 2010-2012 in the perinatal center. Medications were earlier put on to women in residential antenatal clinics and polyclinics. We have also assessed the rationality and safety of such prescriptions.Results.147 cases of AP against AI in pregnant women were registered and analyzed during the research. The most frequently prescribed groups of medications were the following: penicillins – 53 (35.6%) (amoxicillin – 17%, amoxicillin/clavulanate – 15.6%, ampicillin – 2.7%); cephalosporins – 25 (17%) (cefotaxime – 7.5%, ceftriaxone – 5.4%, cefazolin – 2.7%); macrolides – 62 (42.2%) (azithromycin – 24.5%, josamycin – 11.6%, spiramycin – 2.7%), other – 7 (4.8%). It is necessary to underline that in 59 (40.1%) cases prescriptions were regarded as inappropriate (probability of viral infection), in 37 (25.2%) cases –amphibolic. 24 (16.3%) cases of irrational prescriptions were also revealed (banned medication or irrational combination of medications prescribed, violations of administration schedule).Conclusions.Antimicrobials prescribed to pregnant women against airway's infections in out-patient and antenatal clinics were identified as the most frequent. Besides, the high level of irrational prescriptions was marked in following cases: AP against viral infections, violations of administration schedule, etc. This issue requires a further in-depth research. ER -