TY - JOUR T1 - Late-breaking abstract: Immediate effects of cigar smoking on control of breathing among young smokers JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1805 AU - Efstathia Konstantinidi AU - Panagiotis Behrakis AU - Andreas Lappas AU - Anna Tzortzi AU - Charikleia Stathopoulou AU - Miltiades Vssiliou Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1805.abstract N2 - IntroductionImmediate effects of cigar smoking on control of breathing have not been comprehensively investigated yet.Materials and methods50 young smokers (average age=23±4, 32 males, mean pack-years=3.6) using cigarettes and occasionally cigars voluntarily participated in this study. 25 had mild respiratory symptoms (atopic history, mild cough and exercise induced chest tightness) and mild peripheral airways obstruction (FEF25%-75%=74.15% pred., MRS-subgroup). The other 25 had normal dynamic flows and no respiratory complaints (NRS-subgroup). Mouth occlusion pressure at 0.1 s (P0.1), tidal volume(VT), inspiratory time(Ti), expiratory time(TE), period of the respiratory cycle(TTOT), duty cycle(Ti/TTOT) and mean inspiratory and expiratory flow (VT/Ti and VT/TE) were measured before and immediately after 30 minutes of cigar smoking or equal session in the smoking area without smoking (control group). Wilcoxon signed rank and U-Mann-Whitney rank sum tests were performed for the statistical analysis.Results Immediately after 30 minutes of cigar smoking TE and TTOT significantly decreased (-9.27%, p=0.009 and -5.85%, p=0.049) whereas Ti/TE and Ti/TTOT significantly increased (+8.06%, p=0.018 and +4.02%, p=0.021) in the NRS-subgroup. In the MRS-subgroup, only Ti/TTOT was significantly altered (+2.88%, p=0.034). In the whole population (n=50) significant increase of Ti/TE, Ti/TTOT and VT/TE (+6.4%, p=0.006, +3.4%, p=0.002 and +5.8%, p=0.026) and significant decrease of TE and TE/TTOT (-7.5%, p=0.017 and -2.56%, p=0.015) were detected.ConclusionsCigar smoking has immediate effects on respiratory timing but not on P0.1 regardless of respiratory complaints and mild peripheral airways obstruction presence. ER -