%0 Journal Article %A Santosh Deo %A BishnuHari Paudel %A Rita Khadka %A Nirmala Limbu %T Effect of experimental modulation of different mood states on dyspnea %D 2014 %J European Respiratory Journal %P 416 %V 44 %N Suppl 58 %X Dyspnea is the subjective experience of breathing discomfort, commonly reported during intense emotional states, heavy exercise and cardiorespiratory diseases.The objective of the study was to explore the effect of experimentally induced changes in mood on exertional dyspnea during standard exercise stress test.Standard emotional pictures were categorized into positive, negative and neutral picture series. Twenty five healthy male volunteers performed standard exercise stress test using cycle ergometer with simultaneously showing emotional pictures displayed on a monitor in front for 5 min with reporting of dyspnea and recording of respiratory rate and heart rate. In comparison to neutral mood state, there was significant increase in shortness of breathing [4.6(4.2-5.4) vs. 3.4(3.0-3.8)], botherness to shortness of breathing [4.6(4.0-5.8) vs. 3.6(2.8-4.2)], respiratory rate [32.2(29.7-35.3) vs. 28.4(26.6-31.2) cycles/min] and heart rate [116.4 (105.4-128.4) vs. 123(109.9-144.3) beats/min] in negative mood state whereas there was no significant difference in those variables in positive mood state. Likewise, in comparison to negative mood state, there was significant decrease in shortness of breathing [3.2(2.0-3.9) vs. 4.6(4.2-5.4)], botherness to shortness of breathing [3.2(2.2-3.8) vs. 4.6(4.0-5.8)], respiratory rate [29.0(26.3-31.6) vs. 32.2(29.7-35.3) cycles/min] and heart rate [114(102.7-138.7) vs. 123(109.9-144.3) beats/min] in positive mood state. The result suggests that negative mood state increases perceived dyspnea but positive mood state reduces it, indicating its potential psychotherapeutic use that can reduce troublesome dyspnea in patients of cardiorespiratory diseases. %U