RT Journal Article SR Electronic T1 Variables related with a COPD diagnosis trough an active research: On-detect study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1978 VO 44 IS Suppl 58 A1 Rosa Malo de Molina A1 Pedro J. Marcos A1 Ricard Casamor YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/1978.abstract AB Aim: To find variables associated with COPD diagnosis through active research of cases.Methods: Observational, cross-sectional, multicentre study at a primary care setting in Spain. Subjects aged 40 and older were recruited with following criteria: any respiratory symptom, a history of smoking (>10 pack-years), and no previous COPD diagnosis/treatment. In a single visit, consenting patients reported smoking history, symptoms, and comorbidities. Spirometry with reversibility test was conducted (ATS standards). QoL questionnaire (CAT) was completed.Results: 2758 subjects were randomly selected at 368 clinics. 1725 fulfilled study criteria and were analysed. After spirometry test, 793 (46%) patients had a COPD diagnosis. Compared with non-COPD, the COPD patients were older (61.3 vs. 59.1 years p<0.0001), had more frequently a history of lower respiratory tract infections (61.7% vs 48.5%, p<0.0001) and had more comorbidities (76.8% vs 67.7%, p<0.0001). COPD patients also reported an exacerbation (61.3% vs 51.8%, p=0.0001), or hospitalization (14.9% vs 10.0%, p=0.0037) more often in previous year. At the time of the visit, COPD patients were more dyspnoeic (37.1% vs 22.1%, p<0.0001), had a higher incidence of chronic cough (80.6% vs 70.2%, p<0.0001), chronic sputum production (66.2% vs 59.6%, p=0.0064) and scored poorer on quality of life according to the CAT Test (8.1 (7.5) vs 14.8 (7.5), p<0.0001).Conclusion: In this cohort from primary care, a history of lower respiratory tract infections, comorbidities, and previous exacerbations or hospitalizations together with current dyspnea, chronic cough, chronic sputum production, and worse quality of life were all factors associated with a COPD diagnosis.