PT - JOURNAL ARTICLE AU - Sara Lonni AU - Nicola Sverzellati AU - Anna Maria Zanaboni AU - James D. Chalmers AU - Giulia Bonaiti AU - Giulia Suigo AU - Sara Annoni AU - Paola Faverio AU - Alberto Pesci AU - Stefano Aliberti TI - The weight of radiological severity in patients with non-CF bronchiectasis DP - 2014 Sep 01 TA - European Respiratory Journal PG - P4938 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P4938.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P4938.full SO - Eur Respir J2014 Sep 01; 44 AB - In the recently published Bronchiectasis Severity Index (BSI), radiological severity of non-CF bronchiectasis (NCFBE) has been assessed by a modified Reiff score (RS). A better accuracy of the BSI could be obtained if the more comprehensive Bhalla score (BS) will be used. To test this hypothesis, an observational, prospective study was performed on NCFBE patients at the bronchiectasis clinic of the San Gerardo University Hospital, Monza, Italy, during the year 2011. Both modified Reiff and Bhalla scores were calculated from chest HRCT scans by two external radiologists and compared among the BSI. The occurrence of at least one hospitalization for exacerbation during 2011 was the study outcome. Rounded averaged beta-coefficients of the BS identified by a Cox regression analysis were used to award points for the BSI score. The performance of the BSI including either the RS or the BS for hospital admission was assessed using the area under the receiver operator characteristic curve (ROC). A total of 146 consecutive NCFBE patients (48% males; median age: 68 years) were enrolled. Median values of the RS and BS in the study population were 6 and 19, respectively. 0 points were given for a RS <3 and 1 for a RS of 3+, as originally indicated. 0 points were given for a BS of 1-10, 5 points for 11-32 and 8 points for 33+. The ROC of the BSI for the study outcome was 0.88 and 0.87 including the RS or BS, respectively. The use of a more comprehensive score does not seem to improve the weight of radiological severity within the BSI in NCFBE patients.