TY - JOUR T1 - Is propofol must added to midazolam premedication in EBUS-TBNA procedure? JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P3555 AU - Selahattin Oztas AU - Ulku Aka Akturk AU - Levent Alpay AU - Burhan Meydan AU - Hamza Ogün AU - Mahsuk Taylan AU - Murat Yalçinsoy AU - Haluk Calisir AU - Dilek Ernam AU - Metin Gorguner Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P3555.abstract N2 - Introduction, objective: Endobronchial ultrasound -guided transbronchial needle aspiration ( EBUS TBNA ) is a method used in the diagnosis and/or staging of pulmonary diseases. Premedication drugs for sedation are different among centers. Besides the midazolam sedation, use of propofol to suppress the cough reflex and loss of consciousness, provide an acceptable safety profile. In this study we aimed to compare the diagnostic yield and complication of EBUS-TBNA using two method of sedation during the procedure. Materials and Methods: 224 patients who underwent EBUS-TBNA between January 2010 and December 2013 were included into the study. Propofol combined with midazolam administered to 144 patients. Only midazolam ( 0.05 to 0.1mg / kg) was given to 88 patients for sedation. Complications and pathological results were recorded.Results:The mean age of 224 cases were 55.8 ±11.6 years. Diagnostic yield was 77.1% in the group receiving propofol plus midazolam, while 83.8 % were found in the midazolam group.View this table:Table 1:Diagnostic yield of EBUS TBNA procedure in propofol added and not added groupsNo significant difference was seen between two groups (p =0.156).There were not seen any complication in midazolam group, howewer hypoxia and hypotension were seen in propofol added group. Conclusion:Propofol did not appear to contribute additional diagnostic yield in EBUS-TBNA procedure . Propofol is helpful to process to be comfortable, but side effects such as hypoxia and hypotension may be seen rarely. ER -