PT  - JOURNAL ARTICLE
AU  - Urszula Jedynak-Wasowicz
AU  - Ewa Cichocka-Jarosz
AU  - Malgorzata Sladek
AU  - Krzysztof Fyderek
AU  - Grzegorz Lis
TI  - Evaluation of gastroesophageal reflux in children with persistent cough: Correlation between multichannel intraluminal impedance/pH-metry and oropharyngeal pH monitoring
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P4469
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P4469.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P4469.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Objectives:Infections and gastroesophageal reflux (GER) may have the same symptom - cough. Oropharyngeal (OP) pH monitoring is a new method developed to detect supraesophageal gastric reflux.The aim of the study was to assess 1. the prevalence of GER in children with persistent cough and 2. the correlation between multichannel intraluminal impedance/pH-metry (MII/pH) and OP pH monitoring.Methods: 21 children with persistent cough were enrolled into the study (15 boys, mean age 11,9±3,5 yrs). 24-h esophageal MII/pH and OP pH-monitoring were performed simultaneously. OP events were detected for pH thereshold of <5,5. The degree of association between reflux events (RE) measured by MII/pH and OP pH-monitoring was estimated by rank correlation (rho).Results: Upright GER detected by OP pH-monitoring was found in 11 children (52%), and in 4 children (19%) in supine position. Statistics of RE are displayed in table 1. Correlations analysis and Bland-Altman plot revealed that only RE in supine position have good association (rho=0,56).View this table:Table 1. Number of reflux events in children with cough measured by MII/pH and OP pH-monitoring and rank correlation results between methodsConclusion: In coughing children, reflux events detected by MII/pH and OP pH-monitoring could be estimated comparable only in supine position.