TY - JOUR T1 - Utility of bronchoscopy in the rapid diagnosis of miliary tuberculosis JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P2624 AU - Pilar Sanjuán López AU - Marina Blanco Aparicio AU - Iria Vidal García AU - Carmen Montero Martínez Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P2624.abstract N2 - In miliary tuberculosis (TB) sputum smear is often negative or no sample is obtained, this means the need for invasive techniquesAIM: Communicate our experience with the yield of bronchoscopy in rapid diagnosis of miliary TBMETHODS: Retrospective study of patients diagnosed with miliary TB with at least 1 bronchoscopy between 1995-2011. Definitive diagnosis: 1) culture of M. tuberculosis in any sample 2) caseating granuloma in biopsy, with or without Ziehl-Neelsen positive 3) response to treatment for TB. Rapid diagnosis: sputum smear positive or necrotizing granulomas.RESULTS: 42 patients identified. 43% women. Mean age: 46.2 + 8 years. Risk factors for miliary TB: HIV 12%; Alcoholism/hepatic disease 23%; Diabetes mellitus 10%, Immunosuppressive drugs 17%; older than 70 years 17%; others 21%. Diagnostic methods: 20 (48%) patients had spontaneous sputum and culture was positive in 12 (60%). Sputum was induced in 2 (4.8%): stain was negative and culture positive in one.View this table:Table 1: yield of bronchoscopic samplesRapid diagnosis by bronchoscopy was reached in 24 (57%) cases and definitive diagnosis in 35 (83%).CONCLUSIONS: the smears of the BAS and BAL have low diagnostic yield. Transbronchial biopsy is the technique of choice for rapid diagnosis of miliary TB and we recommend its systematic implementation if the risk is acceptable. ER -