RT Journal Article
SR Electronic
T1 Influence of depression in a smoking cessation program
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4452
VO 44
IS Suppl 58
A1 Luciana Pimenta Bento
A1 Telma Sequeira
A1 José Pedro Boléo-Tomé
A1 Ricardo Melo
A1 Cecília Pardal
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P4452.abstract
AB Introduction: Smoking rates amongst depressed patients are higher than in general population. Treating depressed smokers is a challenge due to their dysfunctional emotional regulation and severe withdrawal symptoms.Aim: To understand how depression influenced a tobacco cessation program.Methods: Retrospective study of a cohort of 331 patients followed at our cessation program. Data were collected from revision of case notes. SPSS 21th version was used for statistical analysis.Results: 54.1% patients were male, mean age was 48.7 years; 22.7% of the patients were depressed and 12.3% had history of depression. Amongst depressed individuals, 64% were female. Median number of cigarettes per day was 20, without differences concerning depression status.Regarding Fagerström scale, 135 individuals had high nicotine addiction, with higher rates among depressed patients (56.8% vs 36.5%, p‹0.01). According to HADS, respectively 139 and 67 patients showed significant anxiety and depression. These rates were significantly higher (p‹0.01) amongst depressed individuals. 51 subjects had a high Richmond score (10) and this rate was significantly lower in the depressed group (8% vs 17.7%, p‹0.05).At 6 months, 105 individuals had quit smoking. This rate was significantly lower amongst depressed patients (16% vs 36.3%, p‹0.05), who were more likely (OR: 2.33, 95% CI:1.2-4.8) to continue smoking than non-depressed subjects (p‹0.05). In spite of depression status, varenicline was associated with higher quitting rates (p‹0.05). Similar associations were found in patients with past depression.Conclusion: Our results confirm the negative effect of, not only active depression, but also prior history of depression on tobacco quitting rates.