PT - JOURNAL ARTICLE AU - Logan Thirugnanasothy AU - Sasiharan Sithamparanathan AU - Leslie Mitchell AU - Andrew Fisher AU - James Lordan AU - Paul Corris TI - Outcomes in embolisations of pulmonary arterio-venous malformations DP - 2014 Sep 01 TA - European Respiratory Journal PG - P2329 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/P2329.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/P2329.full SO - Eur Respir J2014 Sep 01; 44 AB - IntroductionPulmonary arterio-venous malformation (AVM) development is an important clinical problem due to the risk of paradoxical embolism and cerebral abscess. To reduce these risks, coil embolisation is recommended.AimsTo establish following embolisation:The degree of improvement in oxygenationThe complication rateThe incidence of further paradoxical embolismMethodsPatients having had an embolisation of pulmonary AVMs from 2002 were identified from our Radiology and lung function databases.ResultsSince 2002, a total of 57 embolisations were done in 42 patients. The mean increase in oxygen saturations was 3.8% ± 4.5%. Of those who had a shunt calculation done before and after embolisation (27/56), the mean reduction in the shunt was 9.2% ± 8.4%. Only one patient in our cohort had a significant complication, the migration of a coil into the left ventricle which was successfully removed surgically. Prior to embolisation, eight patients had experienced a paradoxical event, including stroke (four), cerebral abscess (four) and an ST-elevation Myocardial Infarction (one); one patient had both a previous stroke and cerebral abscess. Following embolisation, only one patient had a further episode of paradoxical embolism; they had not attended clinic following the preceding embolisation.ConclusionOur centre has demonstrated that over the last 12 years, embolisation of pulmonary AVMs has led to a significant reduction in further episodes of paradoxical embolism and only one complication had occurred. The reduction in shunt fraction was similar to previously reported1.References1. Haitjema et al.Embolisation of pulmonary arterio-venous malformations: results and follow up in 32 patients. Thorax 1995 July; 50(7): 719-723.