PT - JOURNAL ARTICLE AU - Jean-Paul Sculier AU - Leclercq Nathalie AU - Anne-Pascale Meert AU - Ingrid C.S. Toth AU - Marianne Paesmans AU - Thierry Berghmans TI - Muldisciplinary conference (MDC), oncological program (OP) and practice guidelines (GL): The experience of the lung cancer (LC) clinic of a cancer hospital DP - 2014 Sep 01 TA - European Respiratory Journal PG - 1925 VI - 44 IP - Suppl 58 4099 - http://erj.ersjournals.com/content/44/Suppl_58/1925.short 4100 - http://erj.ersjournals.com/content/44/Suppl_58/1925.full SO - Eur Respir J2014 Sep 01; 44 AB - Introduction: the ERS taskforce for quality management in LC care has shown the existence of a lot of European GL but with very few studies about their practical application.Aims: to assess in a LC population the application of an OP based on specific GL and to determine the non application (NA) causes.Methods: the charts of all non-pretreated patients managed between 01-2009 and 12-2012 were reviewed (protocol approved by local ethical committee). The procedure for each new treatment consists in presentation in MDC. Proposed treatment is based on OP performed according to European Lung Cancer Working Party GL.Results: At time of analysis, 624 MDC were performed in 354 patients, including 332, 174, 81 and 47 for 1st, 2nd, 3rd and further lines respectively. Main characteristics were: male in 197; adenocarcinoma, squamous and small cell cancer in 187, 79 & 50; median age 62; stages I & II, III and IV in 48, 75 and 228. In 1st line, the rate of MDC was 94% including 88% performed as recommended by OP and 77% of treatments in agreement with GL. For 2nd and 3rd lines, the rates were respectively 93 and 91% (MDC), 90 and 89% (OP), 55 and 63% (GL). In 1st line, main causes for NA of OP treatments were patient refusal or physician choice and for NA of GL lack of appropriate recommendations for specific situations like comorbidities or availability of new therapies not yet addressed by GL. In subsequent lines, NA of GL was mainly due to new drugs.Conclusion: MDC is performed for the huge majority of the patients with a high rate of application of the OP. GL need to be more frequently updated according to new therapies availability.